The Peptides & Compounds Library
Your evidence-based guide to the molecules of longevity. Explore peptides, hormones, supplements, and medications being studied for their impact on healthspan.
Home Remedies
Hormonal Therapies
Hormone Replacement Therapy (HRT) Guide
HRT supplements key hormones like estrogen, helping manage menopause symptoms and support bone, heart, and cognitive health. It's a key therapy for women.
Testosterone Replacement (TRT)
A therapy for low testosterone, TRT can be a game-changer for energy, libido, muscle mass, and mood. It requires careful medical supervision to be safe.
Growth Hormone (GH) Therapy
Prescribed for GH deficiency, this therapy can improve muscle mass and recovery, but its use for general anti-aging is controversial and has risks.
DHEA: The Mother of All Hormones
DHEA is a precursor to sex hormones like estrogen and testosterone. Its levels decline with age, impacting your vitality and resilience to daily stress.
Melatonin for Sleep & as an Antioxidant
More than a sleep aid, melatonin is a master regulator of your body clock and a powerful antioxidant that protects your cells from damage as you sleep.
Pregnenolone: The Master Hormone
This is the starting point for DHEA, testosterone, and estrogen. As the ultimate precursor, pregnenolone is a powerful modulator of brain health and stress.
Thyroid Hormones (T3/T4) Guide
These master regulators of metabolism are key for energy, weight, and vitality. Optimizing thyroid function is essential for maintaining a low biological age.
Anavar (Oxandrolone) for Muscle
Anavar is an oral anabolic steroid known for promoting lean muscle gain and strength without significant water retention, valued in aesthetic contexts.
Winstrol (Stanozolol) Guide
Winstrol is a steroid favored for its ability to produce a hard, dry, and vascular look by increasing strength without adding significant weight or water retention.
HCG for Testosterone Production
HCG (Human Chorionic Gonadotropin) is used to mimic LH, stimulating the testes to produce testosterone and maintain function during or after cycles.
Dianabol (Methandrostenolone)
Dianabol is a famous oral steroid known for its ability to produce rapid gains in muscle mass and strength, but comes with significant health risks.
Deca-Durabolin (Nandrolone)
Deca-Durabolin is an injectable steroid prized for its ability to add quality muscle mass and soothe joints, making it a favorite for off-season bulking cycles.
Trenbolone: The Powerful Anabolic
Trenbolone is one of the most powerful injectable steroids, known for its dramatic effects on muscle hardness, fat loss, and strength. It carries severe risks.
Peptides
BPC-157: The Healing Peptide
Known as 'Body Protection Compound', BPC-157 is a peptide renowned for its ability to accelerate healing in tissues ranging from muscle and tendons to the gut.
CJC-1295 & Ipamorelin Peptide Stack
This popular peptide stack powerfully stimulates the body's own production of growth hormone, mimicking natural release patterns to improve body composition.
GHK-Cu Copper Peptide Guide
A copper peptide renowned for its remarkable skin-rejuvenating and wound-healing properties, making it a star in both cosmetics and regenerative medicine.
Semaglutide & Tirzepatide Guide
These GLP-1 agonists combat obesity and diabetes—two accelerators of aging—by powerfully regulating appetite and blood sugar.
TB-500 (Thymosin Beta-4) Peptide
A systemic healing peptide that promotes cell migration and upregulates actin, accelerating the repair of muscle, tendon, and skin for improved recovery.
Sermorelin Peptide Therapy Guide
A growth hormone secretagogue that encourages your pituitary to produce more HGH naturally. A subtler, safer approach to GH optimization.
MOTS-c: The "Exercise in a Bottle" Peptide
A unique peptide that signals from your mitochondria, helping to regulate metabolism and improve insulin sensitivity. Often called an 'exercise mimetic.'
Epitalon: The Telomere Lengthening Peptide
This peptide is researched for its fascinating ability to activate telomerase, the enzyme that can lengthen telomeres—the protective caps on our DNA.
AOD-9604: The Fat Loss Peptide
A fragment of human growth hormone designed specifically to stimulate fat burning and inhibit fat storage, without affecting blood sugar or growth.
Dihexa: The Nootropic Peptide
A potent nootropic peptide studied for its potential to enhance cognitive function by promoting the formation of new connections between neurons.
DSIP (Delta Sleep-Inducing Peptide)
A neuropeptide designed to promote deeper, more restorative slow-wave sleep. Quality sleep is a cornerstone of recovery, brain health, and healthy aging.
KPV Peptide for Your Inflammation
A potent anti-inflammatory peptide. It is often used topically to treat inflammatory skin conditions like psoriasis and to promote overall wound healing.
Melanotan II for Tanning & Libido
This peptide stimulates melanin production, leading to a skin tan without UV exposure. It is also widely known for its powerful aphrodisiac effects on libido.
NAD+ & Precursors (NMN, NR)
NAD+ is a critical coenzyme for cellular energy and repair that declines with age. Boosting it via precursors is a key strategy in longevity science.
Oxytocin: The "Social Bonding" Hormone
Known as the "love hormone," oxytocin is crucial for social bonding, trust, and empathy. Strong social ties are a key predictor of a long and healthy life.
PT-141 (Bremelanotide) for Libido
A unique peptide that works on the brain to increase libido and sexual arousal, making it different from drugs that only affect blood flow in the body.
Selank: The Anti-Anxiety Peptide
An anxiolytic (anti-anxiety) peptide nasal spray known for promoting a sense of calm and mental stability without causing sedation or brain fog.
Semax: The Nootropic Brain Peptide
A nootropic peptide nasal spray studied for its potential to improve cognitive function, memory, and act as a neuroprotective agent by boosting BDNF.
Thymosin Alpha-1 for Immune Health
An immune-modulating peptide that helps enhance and regulate the function of T-cells, which are the key soldiers in your body's fight against infections.
Tesamorelin for Visceral Fat Loss
A GHRH analog that powerfully reduces visceral fat, the harmful fat around organs, making it a key tool for improving metabolic health and body composition.
IGF-1 LR3 for Muscle Growth
A long-acting version of Insulin-like Growth Factor-1, this potent peptide promotes hyperplasia, the creation of new muscle cells, for significant growth.
Retatrutide: The "Triple G" Peptide
This investigational "tri-agonist" peptide is showing unprecedented levels of weight loss in clinical trials by targeting three distinct metabolic pathways.
Oral Peptides
Tesofensine for Your Weight Loss
An investigational oral medication known for its powerful appetite-suppressing effects, making it a promising candidate for significant weight loss.
MK-677 (Ibutamoren) Peptide
MK-677 is an orally active growth hormone secretagogue that mimics ghrelin, leading to increased GH and IGF-1 levels, improved sleep, and better recovery.
Research Peptides
5-Amino-1MQ for Your Metabolism
This small molecule compound is being researched for its potential to reverse age-related metabolic decline by inhibiting the enzyme NNMT.
Clenbuterol for Fat Loss
Clenbuterol is a powerful stimulant used for its thermogenic properties to increase metabolic rate and promote fat loss, often used in cutting cycles.
Cardarine (GW-501516) Research
Cardarine is a PPARδ receptor agonist researched for its ability to dramatically increase endurance and fat loss by switching the body’s fuel preference to fat.
Nicotine Gum for Cognitive Use
Used responsibly in pure, non-tobacco forms like gum or lozenges, nicotine can act as a powerful nootropic, enhancing focus, alertness, and cognition.
RAD-140 (Testolone) SARM Guide
RAD-140 is a popular SARM (Selective Androgen Receptor Modulator) researched for its potent anabolic effects on muscle and strength, similar to testosterone.
LGD-4033 (Ligandrol) SARM Guide
LGD-4033 is a SARM known for its ability to produce significant gains in lean muscle mass, making it one of the most popular SARMs for bulking phases.
Ostarine (MK-2866) SARM Guide
Ostarine is a mild but effective SARM used for preserving muscle during a fat-loss phase and for promoting lean, dry gains in muscle mass and strength.
Fasoracetam Nootropic Guide
Fasoracetam is a nootropic in the racetam family studied for its ability to enhance memory and cognitive function by modulating GABA and glutamate receptors.
Pharmaceuticals
Metformin and Its Role in Longevity
This first-line diabetes drug has gained fame in longevity by improving insulin sensitivity and activating the AMPK pathway, mimicking some effects of fasting.
Rapamycin (Sirolimus) Longevity Guide
A powerful drug that inhibits the mTOR pathway, a central regulator of cell growth, Rapamycin is a cornerstone of aging research for its ability to extend lifespan.
Acarbose for Your Blood Sugar Control
This medication slows carbohydrate digestion, smoothing out post-meal blood sugar spikes to combat metabolic aging and potentially extend healthspan.
Letrozole: Aromatase Inhibitor
Letrozole is a powerful aromatase inhibitor used to manage estrogen levels, often in conjunction with anabolic cycles, to prevent estrogenic side effects.
Nolvadex (Tamoxifen) SERM Guide
Nolvadex is a Selective Estrogen Receptor Modulator (SERM) used for post-cycle therapy (PCT) to restore natural testosterone production and block estrogen.
Tadalafil (Cialis) for Health
Beyond its use for erectile dysfunction, low-dose daily Cialis is used to improve blood flow, supporting cardiovascular health and athletic performance.
Low Dose Naltrexone (LDN)
LDN is used for its immune-modulating and anti-inflammatory effects. It works by briefly blocking opioid receptors, which upregulates endorphin production.
Arimidex (Anastrozole) Guide
Arimidex is an aromatase inhibitor used to manage estrogen levels during anabolic steroid cycles, preventing side effects like water retention and gynecomastia.
Clomid (Clomiphene) SERM Guide
Clomid is a SERM used for post-cycle therapy (PCT). It stimulates the pituitary to release more gonadotropins, helping to restart testosterone production.
Aspirin for Cardiovascular Health
Low-dose daily aspirin is a well-studied intervention used to reduce the risk of blood clots, heart attacks, and strokes in at-risk populations.
Statins for Cholesterol Control
Statins are a class of prescription drugs that are highly effective at lowering LDL and ApoB cholesterol levels, a cornerstone of heart disease prevention.
Supplements
Spermidine for Cellular Autophagy
A natural polyamine that is a potent inducer of autophagy, the body's cellular cleanup process, helping to clear out age-related cellular damage.
Creatine for Both Muscle and Mind
Famous for building muscle, creatine is also a vital molecule for energy in your brain, making it a cornerstone supplement for physical and cognitive function.
Omega-3 Fatty Acids Longevity Guide
These essential fats are powerfully anti-inflammatory, forming the building blocks of healthy cell membranes and supporting cardiovascular and brain health.
Vitamin D: The Sunshine Vitamin
This 'sunshine vitamin' acts as a hormone, essential for robust immune function, bone health, mood, and controlling inflammation. Deficiency is very common.
Magnesium for Relaxation and More
A critical mineral involved in over 300 enzymatic reactions, magnesium is vital for muscle relaxation, nerve function, energy production, and DNA stability.
Coenzyme Q10 (CoQ10) for Energy
An antioxidant that is essential for energy production within your mitochondria. It serves as the 'spark plug' for your cells, powering their functions.
Resveratrol as a Longevity Supplement
A polyphenol found in grapes and red wine, known for activating sirtuins, a class of proteins linked to longevity and improved metabolic health.
Turmeric (Curcumin) for Your Pain
Curcumin, the active compound in turmeric, is a potent anti-inflammatory and antioxidant that helps combat the chronic inflammation that drives aging.
Probiotics for Your Gut Health
Live beneficial bacteria that support a healthy gut microbiome, which is crucial for digestion, immune function, and reducing systemic inflammation.
Ashwagandha for Your Stress Relief
An adaptogenic herb used in traditional medicine to help the body manage stress, reduce cortisol levels, and improve sleep quality for better recovery.
Fisetin: The Senolytic Supplement
A natural flavonoid found in fruits like strawberries that has gained attention as a potent senolytic, helping to clear out old, 'zombie' cells.
Vitamin E for Skin and Immune Health
A fat-soluble antioxidant that specializes in protecting cell membranes from oxidative damage, which is crucial for skin health and a robust immune system.
Vitamin B12 for Your Energy
Essential for energy production, nerve function, and red blood cell formation. Deficiency is common in older adults and those on plant-based diets.
Vitamin A and Its Use in Retinoids
Crucial for vision, immune function, and skin health. Its derivatives, retinoids, are the gold standard in anti-aging skincare for a very good reason.
Vitamin K2 for Bones and Your Heart
The 'calcium traffic cop' that directs calcium into your bones and away from your arteries, making it essential for skeletal and cardiovascular health.
Zinc for Your Immune Support
An essential mineral for immune function, wound healing, and hormone production. Zinc plays a role in hundreds of critical enzymatic reactions in the body.
Selenium for Thyroid & Immune Health
A trace mineral that acts as a master antioxidant and is crucial for thyroid and immune health, directly impacting metabolism and our defense systems.
Calcium for Your Bone Health
The most abundant mineral in the body, essential for building and maintaining strong bones. It must be balanced with Vitamins D and K2 for optimal effect.
Collagen for Your Skin and Joints
The body's main structural protein, crucial for skin elasticity, joint health, and connective tissue strength. Supplementing helps counteract its decline.
Astaxanthin Antioxidant Guide
A potent antioxidant from algae that gives salmon its pink color. It is studied for its benefits on skin health, eye health, and reducing inflammation.
Alpha-Lipoic Acid (ALA) Explained
A 'universal' antioxidant that works in every cell, supporting metabolic health by improving insulin sensitivity and regenerating other antioxidants.
Vitamin C for Your Health
An essential antioxidant for immune support and a critical cofactor for synthesizing collagen, vital for skin, bone, and connective tissue health.
Methylene Blue Nootropic Guide
Methylene Blue is a fascinating compound that acts as a mitochondrial enhancer and nootropic, improving memory and cellular energy production at low doses.
Taurine: The Longevity Amino Acid
Taurine is an amino acid with powerful antioxidant properties, crucial for cardiovascular health, mitochondrial function, and protecting cells from stress.
Berberine for Blood Sugar
Berberine is a plant extract that rivals metformin in its ability to improve insulin sensitivity and lower blood sugar by activating the AMPK pathway.
Yohimbine HCL for Stubborn Fat
Yohimbine HCL is an alpha-2 antagonist used to target stubborn body fat by blocking receptors that prevent fat release, often used in a fasted state for best results.
TUDCA for Liver Health
TUDCA is a bile salt with potent protective effects on the liver. It helps reduce cellular stress and is often used to support liver function during cycles.
Alpha-GPC for Choline & Focus
Alpha-GPC is a highly bioavailable source of choline, essential for producing the neurotransmitter acetylcholine, which is critical for memory, focus, and learning.
Huperzine A Nootropic Guide
Huperzine A is a cognitive enhancer that works by inhibiting an enzyme that breaks down acetylcholine, leading to higher levels of this neurotransmitter.
Aesthetics
Retinoids (Tretinoin) for Your Skin
The gold standard in dermatology, these Vitamin A derivatives are proven to reduce wrinkles and improve skin texture by boosting collagen production.
Topical Vitamin C Serum Guide
A daily antioxidant serum that protects skin from free radical damage, brightens the complexion, and is essential for building new collagen in the skin.
Hyaluronic Acid for Your Hydration
A moisture-binding superstar that holds 1,000x its weight in water, providing intense hydration to plump the skin and soften fine lines and wrinkles.
Niacinamide (B3) for Your Skin Tone
A true multi-tasker, this form of Vitamin B3 improves the skin's barrier, reduces redness and inflammation, minimizes pores, and helps control oil.
Glycolic Acid for Your Exfoliation
An alpha-hydroxy acid (AHA) that exfoliates the skin's surface, helping to improve texture, fade dark spots, and stimulate new collagen production.