MK-677 (Ibutamoren) Peptide

MK-677, also known as Ibutamoren, is a potent, long-acting, and orally-active growth hormone secretagogue. It mimics the action of ghrelin, the "hunger hormone," by binding to the ghrelin receptors in the brain. This signals the pituitary gland to release powerful pulses of growth hormone (GH). Unlike direct GH injections, this action preserves the natural pulsatility of GH release. The resulting increase in GH and, subsequently, IGF-1 levels, leads to a host of benefits relevant to biological age. Users often report dramatically improved sleep quality and depth, enhanced recovery from exercise, increased muscle mass, and improved skin and hair quality. However, its ghrelin-mimicking effect also means it can significantly increase appetite, which can be a pro or a con depending on the user's goals. It can also cause water retention and, in some individuals, may decrease insulin sensitivity, requiring careful monitoring. By promoting restorative sleep and an anabolic environment, MK-677 can be a powerful tool for supporting a lower biological age when used correctly.