LGD-4033 (Ligandrol) SARM Guide

LGD-4033, also known as Ligandrol, is another popular SARM that is highly regarded for its ability to produce substantial gains in lean muscle mass. It is considered one of the most potent SARMs for bulking purposes. Clinical studies in healthy young men have demonstrated that LGD-4033 can significantly increase lean body mass without adversely affecting prostate-specific antigen (PSA) levels. It works by selectively binding to androgen receptors in muscle and bone, which stimulates anabolism. While it is less androgenic than many steroids, it is still highly suppressive of natural testosterone production, with studies showing a dose-dependent decrease in both total testosterone and HDL ("good") cholesterol. Like all SARMs, it is an investigational drug with no long-term human safety data, and its use is banned by all major sports organizations. A full PCT is essential after a cycle to restore natural hormone function.